PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Rt |
CD1d is a non-polymorphic, MHC class I-like molecule encoded by the CD1D gene, which is a member of the CD1 family of glycoproteins expressed on the surface of various human antigen-presenting cells. It presents lipid antigens, including phospholipids and glycosphingolipids, to a subset of T cells known as invariant natural killer T (iNKT) cells. When activated by CD1d-presented antigens, iNKT cells rapidly produce Th1 and Th2 cytokines, such as interferon-gamma and interleukin-4. CD1d is also involved in the selection and regulation of iNKT cells. Some known ligands for CD1d include α-galactosylceramide (α-GalCer), a compound derived from a marine sponge, and various microbial and self-antigens.
Flow cytometric analysis of Rat CD1d expression on Lewis Rat thymocytes. Lewis Rat thymocytes were stained with FITC Mouse IgG2a, κ Isotype Control (Left panel) or SDT FITC Mouse Anti-Rat CD1d Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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