PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu, Ms, Rt |
Immunoglobulin superfamily member 8 (IGSF8), also known as CD316, is a protein encoded by the IGSF8 gene in humans. It is an innate immune checkpoint that inhibits the cytotoxic activity of natural killer (NK) cells by binding to the Killer Ig-like Receptor KIR3DL2. IGSF8 is a member of the EWI subfamily of the immunoglobulin protein superfamily, containing a single transmembrane domain, an EWI motif, and a variable number of immunoglobulin domains. It interacts with tetraspanins CD81 and CD9, regulating their roles in various cellular functions, including cell migration and viral infection. IGSF8 may also function as a tumor suppressor by inhibiting the proliferation of certain cancers.
WB result of IGSF8 Recombinant Rabbit mAb
Primary antibody: IGSF8 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: HepG2 whole cell lysate 20 µg
Lane 2: Jurkat whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 65 kDa
Observed MW: 72 kDa
This blot was developed with high sensitivity substrate
WB result of IGSF8 Recombinant Rabbit mAb
Primary antibody: IGSF8 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: NIH/3T3 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 65 kDa
Observed MW: 80 kDa
This blot was developed with high sensitivity substrate
WB result of IGSF8 Recombinant Rabbit mAb
Primary antibody: IGSF8 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: C6 whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 65 kDa
Observed MW: 80 kDa
This blot was developed with high sensitivity substrate
您现在的位置：