PBS pH7.4
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
FCM | 1:200 | Ms |
CD244.2 protein, also known as natural killer cell receptor 2B4 isoform 2 precursor, is a type-I transmembrane protein belonging to the signaling lymphocytic activation molecule (SLAM) family. It is encoded by the CD244 gene and primarily expressed in various immune cells such as NK cells, T cells, monocytes, eosinophils, myeloid-derived suppressor cells, and dendritic cells. This protein mainly binds to its ligand CD48, another SLAM family member, to transmit stimulatory or inhibitory signals and regulate immune responses, including NK cell-mediated cytotoxicity, leukocyte activation, and cytokine production. CD244.2 plays a crucial role in the immune system and has potential as a therapeutic target in cancer and other immune-related diseases.
Flow cytometric analysis of C57BL/6 mouse splenocytes labelling Mouse CD244.2 antibody at 1/200 dilution (1 μg) / (Right panel) compared with a Mouse IgG1, κ Isotype Control / (Left panel). Goat Anti-Mouse IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD49b - FITC Antibody separately.