PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
FCM | 5μl per million cells in 100μl volume | Ms |
CD102, also known as intercellular adhesion molecule 2 (ICAM-2), is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is widely expressed on resting lymphocytes, monocytes, platelets, and vascular endothelial cells. CD102 plays a crucial role in immune response by binding to leukocyte integrins such as LFA-1 (CD11a/CD18) and mediating adhesive interactions important for lymphocyte recirculation, antigen-specific immune responses, and natural killer cell-mediated clearance. Additionally, it has been identified as a biomarker for long-lived plasma cells in non-human primates and is involved in maintaining the longevity of these cells in the bone marrow. Elevated levels of CD102 have also been associated with conditions like hemorrhagic fever with renal syndrome and idiopathic pulmonary fibrosis.
Flow cytometric analysis of Mouse CD102 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Pacific Blue™ Rat IgG2a, κ Isotype Control (Black line histogram) or SDT Pacific Blue™ Rat Anti-Mouse CD102 Antibody (Red line histogram) at 5μl/test, cells without incubation with primary antibody and secondary antibody (Blue line histogram) was used as unlabelled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.