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Pacific Blue Rat Anti-Mouse CD102 Antibody (S-R724)

Pacific Blue Rat Anti-Mouse CD102 Antibody (S-R724)

货号: S0B5256
价格: 200
规格: 20T
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD102
  • 分子别名

    Intercellular adhesion molecule 2; Lymphocyte function-associated AG-1 counter-receptor; Icam-2; Icam2
  • 细胞定位

    Membrane
  • Accession

    P35330
  • 克隆号

    S-R724
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2a,k
  • 应用

    FCM
  • 反应种属 ?

    Ms
  • 阳性样本

    C57BL/6 mouse splenocytes
  • 纯化方式

    Protein G
  • 浓度

    50 μg/ml
  • 标记

    Pacific Blue
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 5μl per million cells in 100μl volume Ms
背景介绍
  • CD102, also known as intercellular adhesion molecule 2 (ICAM-2), is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is widely expressed on resting lymphocytes, monocytes, platelets, and vascular endothelial cells. CD102 plays a crucial role in immune response by binding to leukocyte integrins such as LFA-1 (CD11a/CD18) and mediating adhesive interactions important for lymphocyte recirculation, antigen-specific immune responses, and natural killer cell-mediated clearance. Additionally, it has been identified as a biomarker for long-lived plasma cells in non-human primates and is involved in maintaining the longevity of these cells in the bone marrow. Elevated levels of CD102 have also been associated with conditions like hemorrhagic fever with renal syndrome and idiopathic pulmonary fibrosis.

  • 流式分析

    • Flow cytometric analysis of Mouse CD102 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Pacific Blue™ Rat IgG2a, κ Isotype Control (Black line histogram) or SDT Pacific Blue™ Rat Anti-Mouse CD102 Antibody (Red line histogram) at 5μl/test, cells without incubation with primary antibody and secondary antibody (Blue line histogram) was used as unlabelled control. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.