PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5 μl per million cells in 100μl volume | Ms |
CD49b, also known as integrin alpha-2, is a protein encoded by the CD49b gene in humans. It is a subunit of the integrin receptor family, specifically forming the VLA-2 receptor when paired with the beta-1 subunit. This receptor is primarily involved in mediating cell adhesion to collagen and laminin, playing a crucial role in various biological processes such as platelet aggregation, cell migration, and tissue repair. CD49b is expressed on various cell types, including natural killer cells and a subset of T cells, and has been implicated in immune responses and cancer progression. In cancer research, CD49b has been identified as a potential therapeutic target due to its role in promoting cell proliferation and invasion in certain malignancies.
Flow cytometric analysis of Mouse CD49b expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with APC Rat Anti-Mouse NK1.1 Antibody and FITC Rat Anti-Mouse CD49b Antibody at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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