PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
12 months from date of receipt / reconstitution, -20 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
WB | 1:1000 | Hu |
Cystatin C (CysC) is a low molecular weight, non-glycosylated basic protein composed of 120 amino acids, with a molecular weight of approximately 13 kDa. It is a member of the cysteine protease inhibitor superfamily and is produced at a constant rate by all nucleated cells in the body. As an endogenous marker, CysC is freely filtered by the glomeruli, reabsorbed and metabolized in the proximal tubules, and does not return to the bloodstream. Its serum concentration is independent of factors such as age, gender, diet, and muscle mass, making it an ideal indicator for assessing glomerular filtration rate (GFR) and early kidney function impairment. Elevated levels of CysC may indicate decreased kidney function, while its stability and sensitivity make it superior to traditional markers like serum creatinine.
WB result of CysC Recombinant Rabbit mAb
Primary antibody: CysC Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: Molt-4 whole cell lysate 20 µg
Lane 2: U-2 OS whole cell lysate 20 µg
Lane 3: Caco-2 whole cell lysate 20 µg
Lane 4: MDA-MB-231 whole cell lysate 20 µg
Negative control: Molt-4 whole cell lysate
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 16 kDa
Observed MW: 14 kDa