您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
PIK3CG Recombinant Rabbit mAb (S-1981-51)

PIK3CG Recombinant Rabbit mAb (S-1981-51)

货号: S0B1448
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    PIK3CG
  • 分子别名

    Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma (PtdIns-3-kinase subunit p110-gamma; p110gamma); Phosphoinositide-3-kinase catalytic gamma polypeptide; Serine/threonine protein kinase PIK3CG; p120-PI3K
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Cytoplasm, Cell membrane
  • Accession

    P48736
  • 克隆号

    S-1981-51
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG
  • 应用

    WB
  • 反应种属 ?

    Hu, Ms
  • 阳性样本

    Jurkat, K562, RAW264.7
  • 纯化方式

    Protein A
  • 浓度

    0.5 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度 推荐种属
WB 1:1000 Hu, Ms
背景介绍
  • PIK3CG, also known as phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, is a key component of the phosphoinositide 3-kinase (PI3K) family. It encodes a class I catalytic subunit that binds to the p85 regulatory subunit to form the PI3K complex, which catalyzes the conversion of phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), an essential step in cellular signaling. This gene is located on chromosome 7 and is highly expressed in immune cells, playing crucial roles in cell growth, survival, metabolism, and migration. Abnormal expression or mutations in PIK3CG are associated with various diseases, including immune disorders, cancers, and neurological conditions like autism. Additionally, PIK3CG has been implicated as a potential biomarker for diabetic retinopathy and a target for therapeutic interventions.

  • 免疫印迹

    • WB result of PIK3CG Recombinant Rabbit mAb
      Primary antibody: PIK3CG Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: SW480 whole cell lysate 20 µg
      Lane 2: A549 whole cell lysate 20 µg
      Lane 3: Jurkat whole cell lysate 20 µg
      Lane 4: K562 whole cell lysate 20 µg
      Negative control: SW480 whole cell lysate; A549 whole cell lysate
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 126 kDa
      Observed MW: 120 kDa

    • WB result of PIK3CG Recombinant Rabbit mAb
      Primary antibody: PIK3CG Recombinant Rabbit mAb at 1/1000 dilution
      Lane 1: RAW264.7 whole cell lysate 20 µg
      Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
      Predicted MW: 126 kDa
      Observed MW: 120 kDa