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Anti-EGFR Monoclonal Antibody (Cetuximab) (FITC Conjugate)

Anti-EGFR Monoclonal Antibody (Cetuximab) (FITC Conjugate)

货号: S0B1839
价格: 3080
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Human
  • 抗原名称

    EGFR
  • 分子别名

    Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1
  • 细胞定位

    Cell membrane
  • Accession

    P00533
  • 克隆号

    S-SC017
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    IgG1,k
  • 应用

    Blocking of EGFR signaling Functional assays, FCM
  • 反应种属 ?

    Hu
  • 纯化方式

    Protein A
  • 浓度

    1 mg/ml
  • 纯度

    >95% by SDS-PAGE
  • 标记

    FITC
  • 性状

    Liquid
  • 缓冲体系

    PBS, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 稀释度

    [{"application": "ELISA", "dilution": "", "species": ""}, {"application": "Sandwich ELISA", "dilution": "", "species": ""}, {"application": "CLIA", "dilution": "", "species": ""}, {"application": "Lateral Flow", "dilution": "", "species": ""}, {"application": "Dot Blot", "dilution": "", "species": ""}, {"application": "WB", "dilution": "", "species": ""}, {"application": "IP", "dilution": "", "species": ""}, {"application": "IHC-P", "dilution": "", "species": ""}, {"application": "ICC", "dilution": "", "species": ""}, {"application": "IF", "dilution": "", "species": ""}, {"application": "ICFCM", "dilution": "", "species": ""}, {"application": "FCM", "dilution": "", "species": ""}, {"application": "mIHC", "dilution": "", "species": ""}]
背景介绍
  • Cetuximab is a monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR) which is present on the surface of some cancer cells. Cetuximab binds to the receptor, preventing epidermal growth factor (EGF) from binding to it and stimulating growth of the cancer cells. Cetuximab is used to treat squamous cell cancer of the head and neck. Cetuximab is commonly used alongside chemotherapy as a first line approach to cancer that has spread or is recurring. It is also used alongside radiation therapy in localized disease. Patients with metastatic colorectal cancer that expresses EGFR may be treated with cetuximab in combination with chemotherapy or cetuximab may be given as a single therapy to patients who have failed to respond to irinotecan- and oxaliplatin-based regimens.