PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Ms |
CD205, also known as DEC-205, is a type I C-type lectin receptor and a member of the macrophage mannose receptor family. It is primarily expressed on dendritic cells (DCs), cortical thymic epithelial cells, and some leukocyte sub-populations. This receptor is involved in antigen uptake, processing, and presentation, playing a crucial role in the immune system. CD205 has a unique pH-dependent conformational change, allowing it to efficiently capture and internalize antigens in an acidic environment. Due to its high antigen-presenting efficiency, CD205 is widely used in immunotherapy, particularly in the development of antiviral and antitumor vaccines.
Flow cytometric analysis of Mouse CD205 expression on BALB/c mouse bone marrow. BALB/c mouse bone marrow was stained with Pacific Blue™ Rat Anti-Mouse Ly-6G/Ly-6C Antibody and either Alexa Fluor® 647 Rat IgG2a, κ Isotype Control (Left panel) or SDT Alexa Fluor® 647 Rat Anti-Mouse CD205 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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