PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Hu |
CD200, also known as OX-2, is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is widely expressed on various cell types, including B cells, T cells, dendritic cells, neurons, and endothelial cells. CD200 primarily functions through its interaction with CD200R, a receptor expressed on myeloid cells, T cells, and other immune cells. This interaction suppresses T-cell-mediated immune responses, reduces the production of inflammatory cytokines, and promotes immune tolerance. In the context of cancer, CD200 expression on tumor cells can lead to immune evasion by inhibiting antitumor T-cell responses. Additionally, CD200 plays a crucial role in maintaining immune homeostasis and is involved in various autoimmune and inflammatory diseases.
Flow cytometric analysis of Human CD200 expression on human PBMC (human peripheral blood mononuclear cells). Human PBMC were stained with Brilliant Violet 421™ Mouse Anti-Human CD19 Antibody and either FITC Mouse IgG1, κ Isotype Control (Left panel) or SDT FITC Mouse Anti-Human CD200 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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