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Rat Anti-Mouse CD205 Antibody (S-R673)

Rat Anti-Mouse CD205 Antibody (S-R673)

货号: S0B5154
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD205
  • 分子别名

    Lymphocyte antigen 75; Ly-75; DEC-205; Ly75
  • 细胞定位

    Membrane
  • Accession

    Q60767
  • 克隆号

    S-R673
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2a,k
  • 应用

    FCM
  • 反应种属 ?

    Ms
  • 阳性样本

    BALB/c mouse bone marrow
  • 纯化方式

    Protein G
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 1:2000 Ms
背景介绍
  • CD205, also known as DEC-205, is a type I C-type lectin receptor and a member of the macrophage mannose receptor family. It is primarily expressed on dendritic cells (DCs), cortical thymic epithelial cells, and some leukocyte sub-populations. This receptor is involved in antigen uptake, processing, and presentation, playing a crucial role in the immune system. CD205 has a unique pH-dependent conformational change, allowing it to efficiently capture and internalize antigens in an acidic environment. Due to its high antigen-presenting efficiency, CD205 is widely used in immunotherapy, particularly in the development of antiviral and antitumor vaccines.

  • 流式分析

    • Flow cytometric analysis of BALB/c mouse bone marrow labelling Mouse CD205 antibody at 1/2000 (0.1 μg) dilution/ (Right panel) compared with a Rat IgG2a, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Cells were stained with Ly-6G/Ly-6C - Pacific Blue™ Antibody separately.