PBS pH7.4
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
FCM | 1:2000 | Ms |
CD205, also known as DEC-205, is a type I C-type lectin receptor and a member of the macrophage mannose receptor family. It is primarily expressed on dendritic cells (DCs), cortical thymic epithelial cells, and some leukocyte sub-populations. This receptor is involved in antigen uptake, processing, and presentation, playing a crucial role in the immune system. CD205 has a unique pH-dependent conformational change, allowing it to efficiently capture and internalize antigens in an acidic environment. Due to its high antigen-presenting efficiency, CD205 is widely used in immunotherapy, particularly in the development of antiviral and antitumor vaccines.
Flow cytometric analysis of BALB/c mouse bone marrow labelling Mouse CD205 antibody at 1/2000 (0.1 μg) dilution/ (Right panel) compared with a Rat IgG2a, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Cells were stained with Ly-6G/Ly-6C - Pacific Blue™ Antibody separately.