PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Hu |
CD7, also known as GP40 or T-cell antigen CD7, is a 40 kDa transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is encoded by the CD7 gene located on chromosome 17 and is expressed on the surface of T cells, natural killer (NK) cells, and their precursors. CD7 plays a crucial role in immune regulation by participating in T-cell activation, providing co-stimulatory signals, and facilitating cell adhesion. It is one of the earliest antigens to appear on T-lymphocyte lineage cells and is highly expressed in various stages of T, B, and myeloid cell differentiation. Additionally, CD7 is involved in T-cell infiltration in tumors, making it an important target for cancer immunotherapy.
Flow cytometric analysis of Human CD7 expression on human peripheral blood cells. Human peripheral blood cells were stained with Alexa Fluor® 647 Mouse Anti-Human CD3 Antibody and either Pacific Blue Mouse IgG1, κ Isotype Control (Left panel) or SDT Pacific Blue Mouse Anti-Human CD7 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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