PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用 | 稀释度 | 推荐种属 |
---|---|---|
FCM | 5μl per million cells in 100μl volume | Rt |
CD44H is the standard isoform of the CD44 protein, a widely expressed cell surface glycoprotein that plays a crucial role in cell adhesion, migration, and interaction with the extracellular matrix. It is the most common form of CD44, encoded by exons 1–5, 16, 17, and 19, and lacks the variable exons that characterize other CD44 isoforms. CD44H is expressed in various cell types, including immune cells and cells of the central nervous system. It primarily functions through binding to hyaluronic acid (HA), facilitating cell adhesion, and mediating cellular responses to the extracellular environment. This standard form is essential for maintaining tissue integrity and regulating cell behavior in both physiological and pathological conditions.
Flow cytometric analysis of Rat CD44H expression on Lewis Rat splenocytes. Lewis Rat splenocytes were stained with Brilliant Violet 605™ Mouse Anti-Rat CD3 Antibody and either Pacific Blue Mouse IgG2a, κ Isotype Control (Left panel) or SDT Pacific Blue Mouse Anti-Rat CD44H Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.