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Pacific Blue Mouse Anti-Rat CD44H Antibody (S-R623)

Pacific Blue Mouse Anti-Rat CD44H Antibody (S-R623)

货号: S0B5129
价格: 450
规格: 20T
介绍: -
其他: -
产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    CD44H
  • 分子别名

    CD44 antigen; Extracellular matrix receptor III (ECMR-III); GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1 (PGP-1); Phagocytic glycoprotein I (PGP-I); CD44
  • 细胞定位

    Secreted, Cell membrane
  • Accession

    P26051
  • 克隆号

    S-R623
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG2a,k
  • 应用

    FCM
  • 反应种属 ?

    Rt
  • 阳性样本

    Lewis Rat splenocytes
  • 纯化方式

    Protein A
  • 浓度

    50 μg/ml
  • 标记

    Pacific Blue
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 5μl per million cells in 100μl volume Rt
背景介绍
  • CD44H is the standard isoform of the CD44 protein, a widely expressed cell surface glycoprotein that plays a crucial role in cell adhesion, migration, and interaction with the extracellular matrix. It is the most common form of CD44, encoded by exons 1–5, 16, 17, and 19, and lacks the variable exons that characterize other CD44 isoforms. CD44H is expressed in various cell types, including immune cells and cells of the central nervous system. It primarily functions through binding to hyaluronic acid (HA), facilitating cell adhesion, and mediating cellular responses to the extracellular environment. This standard form is essential for maintaining tissue integrity and regulating cell behavior in both physiological and pathological conditions.

  • 流式分析

    • Flow cytometric analysis of Rat CD44H expression on Lewis Rat splenocytes. Lewis Rat splenocytes were stained with Brilliant Violet 605™ Mouse Anti-Rat CD3 Antibody and either Pacific Blue Mouse IgG2a, κ Isotype Control (Left panel) or SDT Pacific Blue Mouse Anti-Rat CD44H Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.