PBS
12 months from date of receipt / reconstitution, 4 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| IHC-P | 1:1000 | Hu |
| IF | 1:1000 | Hu |
NaPi2b, also known as SLC34A2, is a sodium-dependent phosphate transporter encoded by the SLC34A2 gene and is a member of the SLC34 family. It is an eight-transmembrane protein that plays a crucial role in phosphate homeostasis by facilitating the trans-epithelial transport of phosphate. NaPi2b is highly expressed in various cancers, including non-small cell lung cancer (NSCLC), ovarian cancer, and papillary thyroid carcinoma, making it a promising target for cancer diagnosis and therapy. In normal tissues, its expression is limited, which further highlights its potential as a therapeutic target. Functionally, NaPi2b is involved in dietary phosphate absorption in the small intestine and surfactant synthesis in lung alveoli.
IHC shows positive staining in paraffin-embedded human lung. Anti-NaPi2b/SLC34A2 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
Negative control: IHC shows negative staining in paraffin-embedded human skeletal muscle. Anti-NaPi2b/SLC34A2 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human endometrial cancer. Anti-NaPi2b/SLC34A2 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human lung adenocarcinoma. Anti-NaPi2b/SLC34A2 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human ovarian cancer. Anti-NaPi2b/SLC34A2 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human thyroid cancer. Anti-NaPi2b/SLC34A2 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IF shows positive staining in paraffin-embedded human endometrial cancer. Anti- NaPi2b/SLC34A2 antibody was used at 1/1000 dilution (Green) and incubated overnight at 4°C. Goat polyclonal Antibody to Rabbit IgG - H&L (Alexa Fluor® 488) was used as secondary antibody at 1/1000 dilution. Counterstained with DAPI (Blue). Heat mediated antigen retrieval with EDTA buffer pH9.0 was performed before commencing with IF staining protocol.
Expression of NaPi2b/SLC34A2 in tumor tissue.
Expression of NaPi2b/SLC34A2 in human tissue.
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