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Alexa Fluor® 647 Mouse Anti-Human CD36 Antibody (S-R617)

Alexa Fluor® 647 Mouse Anti-Human CD36 Antibody (S-R617)

货号: S0B5081
价格: 650
规格: 20T
介绍: -
其他: -
产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    CD36
  • 分子别名

    Platelet glycoprotein 4; Fatty acid translocase (FAT); Glycoprotein IIIb (GPIIIB); Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV (GPIV); Thrombospondin receptor; GP3B; GP4
  • 细胞定位

    Cell membrane
  • Accession

    P16671
  • 克隆号

    S-R617
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG1,k
  • 应用

    FCM
  • 反应种属 ?

    Hu
  • 阳性样本

    human peripheral blood
  • 纯化方式

    Protein G
  • 浓度

    50 μg/ml
  • 标记

    Alexa Fluor® 647
  • 性状

    Liquid
  • 缓冲体系

    PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
稀释度
应用 稀释度 推荐种属
FCM 5μl per million cells in 100μl volume Hu
背景介绍
  • CD36 is a transmembrane glycoprotein that serves as a key fatty acid transporter and sensor, playing a crucial role in lipid metabolism. It is involved in the recognition and phagocytosis of lipids by macrophages and has been implicated in inflammatory responses and cardiovascular diseases. CD36 is also expressed in various immune cells and has been shown to regulate autophagy. Additionally, it is highly expressed in several types of cancer, where it promotes tumor progression by facilitating fatty acid uptake, epithelial-mesenchymal transition (EMT), and resistance to anticancer drugs. CD36 has emerged as a potential therapeutic target for metabolic diseases, cardiovascular conditions, and cancer.

  • 流式分析

    • Flow cytometric analysis of Human CD36 expression on human peripheral blood. Human peripheral blood was stained with Brilliant Violet 605™ Mouse Anti-Human HLA-DR Antibody and either Alexa Fluor® 647 Mouse IgG1, κ Isotype Control (Left panel) or SDT Alexa Fluor® 647 Mouse anti-Human CD36 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.