PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| FCM | 5μl per million cells in 100μl volume | Hu |
CD303, also known as BDCA-2 or CLEC4C, is a 38 kD type II transmembrane glycoprotein and a member of the C-type lectin superfamily. It is specifically expressed on plasmacytoid dendritic cells (pDCs) and plays a crucial role in antigen capture and processing, as well as in cell adhesion and signaling. CD303 is involved in the presentation of antigens to T cells and can mediate the inhibition of IFN-α/β expression in pDCs when cross-linked. This molecule is also a potential therapeutic target in diseases such as systemic lupus erythematosus due to its role in immune regulation.
Flow cytometric analysis of Human CD303 expression on human PBMC (human peripheral blood mononuclear cells). Human PBMC were stained with PE/Cy7 Mouse Anti-Human CD123 Antibody and either FITC Mouse IgG2a, κ Isotype Control (Left panel) or SDT FITC Mouse Anti-Human CD303 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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