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Rat Anti-Mouse CD184 Antibody (S-R670)

Rat Anti-Mouse CD184 Antibody (S-R670)

货号: S0B5104
价格: 600
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    CD184
  • 分子别名

    C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor (LESTR); Pre-B-cell-derived chemokine receptor (PB-CKR); Stromal cell-derived factor 1 receptor (SDF-1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4
  • 细胞定位

    Cell membrane, Cell junction, Lysosome
  • Accession

    P70658
  • 克隆号

    S-R670
  • 抗体类型

    Rat mAb
  • 抗体同种型

    IgG2b,k
  • 应用

    FCM
  • 反应种属 ?

    Ms
  • 阳性样本

    C57BL/6 mouse thymocytes
  • 纯化方式

    Protein G
  • 浓度

    2 mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

稀释度
应用 稀释度 推荐种属
FCM 5μl per million cells in 100μl volume Ms
背景介绍
  • CD184, also known as CXCR4 or Fusin, is a seven-transmembrane G protein-coupled receptor that plays a crucial role in various physiological processes. It is widely expressed on hematopoietic cells, including lymphoid and myeloid precursor cells, megakaryocytes, and endothelial cells. Its natural ligand is stromal cell-derived factor-1 (SDF-1), a C-X-C chemokine that induces chemotaxis and enhances intracellular signaling through calcium ion influx and MAPK activation.

  • 流式分析

    • Flow cytometric analysis of C57BL/6 mouse thymocytes labelling Mouse CD184 antibody at 1/200 (1 μg) dilution/ (Right panel) compared with a Rat IgG2b, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 647 was used as the secondary antibody. Then cells were stained with CD4 - Brilliant Violet 421™ Antibody separately.