PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 | 推荐种属 |
|---|---|---|
| WB | 1:1000 | Hu |
CD209, also known as DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Non-integrin), is a C-type lectin receptor primarily expressed on the surface of dendritic cells, macrophages, and certain endothelial cells. It plays a crucial role in the innate immune system by recognizing and binding to a wide range of pathogens, including viruses, bacteria, and fungi. CD209 is involved in mediating antigen endocytosis and degradation, facilitating the interaction between dendritic cells and T cells, and influencing immune responses. Additionally, it has been implicated in the binding of HIV-1 gp120, contributing to viral entry and infection. Research also suggests that CD209 may regulate macrophage polarization and neutrophil development, highlighting its importance in both innate and adaptive immunity.
WB result of CD209 Recombinant Rabbit mAb
Primary antibody: CD209 gamma Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: untreated THP-1 whole cell lysate 20 µg
Lane 2: THP-1 treated with 100 ng/ml GM-CSF and 50 ng/ml hIL-4 for 7 days whole cell lysate 20 µg
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 46 kDa
Observed MW: 45~55 kDa
您现在的位置：