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LILRA3/CD85e Fc Chimera Protein, Human

LILRA3/CD85e Fc Chimera Protein, Human

货号: UA010041
价格: 3600
规格: 100μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • Accession

    Q8N6C8
  • 表达序列

    Gly24-Glu439, with C-terminal human IgG Fc GPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVSGAAETLSPPQNKSDSKAGEIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
  • 表达宿主

    HEK293
  • 分子量

    85-95 kDa(Reducing)
  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    Human Fc Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, pH7.4
  • 溶解方法

    Reconstitute at 0.1-1mg/mL according to the size in ultrapure water after rapid centrifugation.
  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.
  • 稀释度

背景介绍
  • LILRA3(Leukocyte Immunoglobulin Like Receptor A3, also known as LIR4, ILT6, or CD85e) is produced by monocytes and macrophages in the form of a soluble molecule. It is a highly glycosylated protein secreted. LILRA3 located in chromosome 19q 13.4, is the only LILR showing genetic diversity, with one or two LILRA3 allelic deletions of 6.7k bp. It is belongs to the LILR family of highly homologous activating and inhibitory cell surface receptors. LILRs includes activating (LILRA1, LILRA2, LILRA3) and inhibitory (LIRB1, LILRB2, LILRB3, LILRB4, LILRB5) isoforms. LILRA3 may bind the same or similar ligands which act as an antagonist or agonist to other members of LILRs. LILRA3 has potential significant functions in autoimmune diseases, such as Psoriasis, multiple sclerosis, Sjogren's syndrome and rheumatoid arthritis. 

  • 电泳JSON

    • 1μg(R: reducing conditions, N: non-reducing conditions)