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Angiopoietin-1(277-498) His Tag Protein, Mouse

Angiopoietin-1(277-498) His Tag Protein, Mouse

货号: UA010234
价格: 2400
规格: 100μg
介绍: -
其他: -
产品规格
  • 物种

    Mouse
  • 分子别名

    Angiopoietin-1, AGP1, AGPT, Ang1, ANG-1, ANGPT1
  • Accession

    O08538
  • 表达序列

    Arg277-Phe498, with C-terminal His
  • 表达宿主

    HEK293
  • 分子量

    28-33kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    His Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, pH7.4
  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
  • 文献引用

    1、Yoon J C. et al. (2000) Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol Cell Biol. 20(14): 5343-5349.

  • 稀释度

背景介绍
  • This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability.
  • 电泳JSON

    • 2μg (R: reducing conditions, N: non-reducing conditions).