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M-CSF Protein, Mouse

M-CSF Protein, Mouse

货号: UA040128
价格: 720
规格: 10μg
介绍: -
其他: -
产品规格
  • 物种

    Mouse
  • 分子别名

    M-CSF; CSF-1; Macrophage Colony Stimulating Factor
  • Accession

    P07141-1
  • 表达序列

    Lys33-Pro187

  • 表达宿主

    E.coli
  • 分子量

    18.2 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 活性

    <2ng/ml
  • 标记

    Unconjugated
  • 标签

    No Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    20mM Tris,200mM NaCl,pH8.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Cosman D, Wignall J, Anderson D, et al. 1988. Behring Inst Mitt: 15-26.

  • 稀释度

背景介绍
  • Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), is a hematopoietic growth factor. It can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of several diseases, including breast and endometrial cancers.

  • 生物活性JSON

    • Measured in a cell proliferation assay using Murine M-NFS-60 cells, the EC50 for this effect is less than 2ng/ml.

  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).

  • ELISA

    • Immobilized M-CSF Protein, Mouse (Cat. No. UA040128) at 2.0μg/mL (100μL/well) can bind M-CSFR mFc Chimera, Mouse(Cat. No. UA010188) with EC50 of 5.52-8.06 ng/ mL.