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Biotinylated CD47 Fc Chimera Protein, Human

Biotinylated CD47 Fc Chimera Protein, Human

货号: UA010007
价格: 2700
规格: 25μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Biotinylated CD47 Fc Chimera protein;antigen identified by monoclonal 1D8, Antigenic surface determinant protein OA3, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 antigen, CD47 glycoprotein, CD47 molecule, CD47, IAP, IAPintegrin associated protein, Integrin-associated protein, leukocyte surface antigen CD47, MER6, MER6integrin-associated signal transducer, OA3, Protein MER6, Rh-related antigen

  • Accession

    Q08722

  • 表达序列

    Gln19-Pro139, with C-terminal Human IgG1 Fc&Avi tag

  • 表达宿主

    HEK293

  • 分子量

    110 kDa(Non-reducing)

  • 纯度

    ＞95%, by SDS-PAGE under reducing conditions

  • 内毒素含量

    <0.2EU/μg

  • 标记

    Biotin

  • 标签

    Human Fc Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS pH7.2, 5% trehalose

  • 溶解方法

    Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍

  • CD47 (Cluster of Differentiation 47), also known as integrin associated protein (IAP), is a transmembrane protein that in humans is encoded by the CD47 gene. It belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. Also CD47 is ubiquitously expressed in human cells and has found to be overexpressed in many different tumor cells.

  • 生物活性JSON

    • Immobilized Human SIRP-α Fc Chimera, Human (Cat. No. UA010005) at 1 μg/mL (100μL/well) can bind Biotinylated Human CD47 Fc Chimera (Cat. No. UA010007) with EC50 of 0.067 μg/mL.

  • 电泳JSON

    • Biotinylated Recombinant Human CD47, Fc Chimera 0.5μg on SDS-PAGE under Non-reducing condition. The purity is greater than 95%.