Biotinylated Fc γ RIV/CD16-2 His&Avi Tag Protein, Mouse
货号: UA010350
价格: 2800
规格: 25μg
介绍: -
其他: -
产品规格
物种
Mouse
分子别名
Fc gamma RIV, CD16-2, Fcgr4
Accession
A0A0B4J1G0
表达序列
Gly21-Gln203, with C-terminal 8*His&Avi tag
GLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQ GGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE
表达宿主
HEK293
分子量
28-35kDa
纯度
>95% by SDS-PAGE
内毒素含量
<1EU/μg
标记
Biotin
标签
Avi Tag, His Tag
性状
Lyophilized Powder
缓冲体系
PBS, pH7.4
溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用
1、Hirano M. et al. (2007) IgEb immune complexes activate macrophages through FcγRIV binding. Nature Immunology. 8: 762-771.
稀释度
背景介绍
Fc γ RIV (Low affinity immunoglobulin gamma Fc region receptor IV), also known as CD16-2 (Fc γ RIV), belongs to the Fc γ receptor family. There are three types of Fc γ receptors: Fc γ RI (CD64), Fc γ RII (CD32) and Fc γ RIII (CD16). Fc γ RI (CD64) has a high affinity for IgG monomer, while Fc γ RII (CD32) and FC γ RIII (CD16) have a relatively low affinity for IgG. Human CD16 is encoded by two genes, Fc γ RIIIA and Fc γ RIIIB. The gene sequence of CD16-2 is more similar to that of human Fc γ RIIIA protein. The combination of FcγRIV and IgG2a can promote bone cell differentiation. The combination of FcγRIV and IgE can promotes macrophage-mediated phagocytosis, antigen presentation, and proinflammatory cytokine production.
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