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Betacellulin Protein, Human

Betacellulin Protein, Human

货号: UA040071
价格: 810
规格: 10μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    Betacellulin, BTC
  • Accession

    P35070
  • 表达序列

    Asp32-Tyr111
  • 表达宿主

    E.coli
  • 分子量

    12-16kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    No Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, pH7.4
  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.
  • 文献引用

    1、Yamamoto K. et al. (2000) Recombinant human betacellulin promotes the neogenesis ofβ-Cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion. Diabetes. 49(12): 2021-2027.

  • 稀释度

背景介绍
  • Betacellulin (BTC) is a member of the epidermal growth factor (EGF) family. Betacelluli is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum. It is synthesized primarily as a transmembrane precursor, which is then processed to a mature molecule by proteolytic events. Betacellulin signals through the EGF receptor.

  • 生物活性JSON

    • Measured in a cell proliferation assay using Balb/c 3T3 mouse fibroblast cells. The EC50 for this effect is less than 1ng/ml.
  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).