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FGF-10 Protein, Mouse

货号: UA040076

价格: 950

规格: 10μg

介绍: -

其他: -

产品规格

物种

Mouse
分子别名

FGF-10, Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2, KGF2
Accession

O35565
表达序列

Ser62-Thr209
表达宿主

E.coli
分子量

17kDa
纯度

>95% by SDS-PAGE & RP-HPLC
内毒素含量

<1EU/μg
标记

Unconjugated
标签

No Tag
性状

Lyophilized Powder
缓冲体系

20mM Tris, 50mM NaCl, 2mM DTT, pH8.0
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

1、Hubert F. et al. (2022) FGF10 promotes cardiac repair through a dual cellular mechanism increasing cardiomyocyte renewal and inhibiting fibrosis. Cardiovasc Res. 118(12): 2625-2637.
2、Sun W. et al. (2019) Cytokine fibroblast growth factor 10 (FGF10) polymorphisms are associated with risk of myopia in young children. J Cell Biochem. 120(9): 15241-15247.

背景介绍

Fibroblast growth factor 10 (FGF-10), a secreted heparin-binding protein, is a member of the fibroblast growth factor (FGF) family and is also known as Keratinocyte Growth Factor-2 (KGF-2). FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies revealed that genetic variants of FGF10 were associated with extreme myopia in adults.