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PlGF-2/PLGF/PGF Protein, Mouse

PlGF-2/PLGF/PGF Protein, Mouse

货号: UA040136
价格: 1080
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Mouse

  • 分子别名

    PGF, PLGF, PlGF2, PlGF, PGFL, SHGC-10760

  • Accession

    P49764-1

  • 表达序列

    Val19-Pro158, with C-terminal 8*His VHSQGALSAGNNSTEVEVVPFNEVWGRSYCRPMEKLVYILDEYPDEVSHIFSPSCVLLSRCSGCCGDEGLHCVPIKTANITMQILKIPPNRDPHFYVEMTFSQDVLCECRPILETTKAERRKTKGKRKRSRNSQTEEPHPGGGSHHHHHHHH

  • 表达宿主

    HEK293

  • 分子量

    25-33kDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Review ProgRetin Eye Res.2019 Mar;69:116-136.Epub 2018 Oct 30.

  • 稀释度

背景介绍

  • Placental growth factor (PGF), also known as vascular endothelial growth factor-related proteins PLGF and PlGF2, is a member of the vascular endothelial growth factor (VEGF) family. PlGF is a three-dimensional structure composed of 149 amino acids. PlGF is a dimeric glycoprotein formed by a 69kD α chain and a 34kD β chain connected by disulfide bond, with a unique cystine junction. These junctions are characterized by eight spatially conserved cysteines that are involved in intramolecular and intermolecular disulfide bond formation. PlGF is a pleiotropic factor affects different cell types and regulates various biological responses.PGF is not only activated during angiogenesis and endothelial cell growth, stimulating their proliferation and migration, but also promoting cell tumor growth.

  • 生物活性JSON

    • Measured in a cell proliferation assay using Balb/c 3T3 mouse fibroblast cells, the EC50 for this effect is less than 5ng/ml.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).