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CD97/AGRE5 His Tag Protein, Human

货号: UA010736

价格: 3020

规格: 100μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

CD97 Protein, Human; TM7LN1 Protein, Human
Accession

P48960-2
表达序列

Gln21-Gln398, with C-10*His
表达宿主

HEK293
分子量

50-72kDa (Reducing)
纯度

＞95% by SDS-PAGE
内毒素含量

<0.1EU/μg
标记

Unconjugated
标签

His Tag
性状

Lyophilized Powder
缓冲体系

PBS, pH7.4.
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

1.nature scientific reports articles article Article Open access Published: 06 February 2019.

背景介绍

CD97 is a member of the g protein-coupled receptor epidermal growth factor-7 transmembrane (EGF-TM7) subfamily and is involved in tumor cell adhesion, migration, angiogenesis, and apoptosis. CD97 is a receptor predominantly expressed in leukocytes and belongs to a new group of seven-span transmembrane molecules, which is also designed EGF-TM7 family. The family members are characterized by an extended extracellular region with several N-terminal epidermal growth factor-like domains two of which contain a calcium-binding site. Studies have shown that CD97 has been recognized as an effective target for the treatment of acute myeloid leukemia (AML) and glioblastoma.