Ser21-Gly295 with His Tag at C-Terminus
PBS, 5% trehalose, PH7.4
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1.Meyers, J.H. et al. (2005) Trends Mol. Med. 11:1471.
2.Kuchroo, V.K. et al. (2003) Nat. Rev. Immunol. 3:454.
3.Mariat, C. et al. (2005) Phil. Trans. R. Soc. B 360:1681.
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) or T cell immunoglobulin mucin 1 (TIM-1), is an integral membrane glycoprotein. KIM-1 is widely expressed, with the highest levels found in the kidney and testis. It is recognized as a major susceptibility gene for asthma, allergy, and autoimmunity in humans. IgA1lambda, a specific ligand of KIM-1, has been shown to have a synergistic effect in virus-receptor interactions. KIM-1 is implicated in the pathogenesis of acute kidney injury and has been confirmed as a biomarker of renal dysfunction in human urine. Additionally, KIM-1 is a novel regulatory molecule of flow-induced calcium signaling
1μg (R: reducing condition, N: non-reducing condition).
The purity of TIM1/HAVCR1 His Tag Protein, Human is greater than 95% as determined by SEC-HPLC.