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NCAM-1/CD56 Fc Chimera Protein, Human

NCAM-1/CD56 Fc Chimera Protein, Human

货号: UA010813
价格: 1280
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    CD56, MSK39, NCAM1, N-CAM-1
  • Accession

    P13591-2
  • 表达序列

    Leu20-Gly718 with Human IgG1 Fc at C-Terminus

  • 表达宿主

    HEK293
  • 分子量

    110-130kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 活性

    Immobilized NCAM-1/CD56 Fc Chimera Protein, Human (Cat. No. UA010813) at 2.0μg/mL (100μL/well) can bind Biotinylated Lorvotuzumab with EC50 of 8.22-12.4 ng/mL.
  • 标记

    Unconjugated
  • 标签

    Human IgG1 Fc
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, PH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. 
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.  
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1、Guven A. et al. (2021) Development and validation of an immunoassay for quantification of NCAM-1 in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 197: 113981.

  • 稀释度

背景介绍
  • Neural Cell Adhesion Molecule 1 (NCAM-1), a multifunctional member of the immunoglobulin superfamily, is expressed on the surfaces of neurons, glial cells, skeletal muscle, and natural killer cells. NCAM-1 plays a role in cell-cell adhesion and is crucial for the development of the nervous system. It is also involved in the expansion of T cells and dendritic cells, which are key players in immune surveillance.

  • 电泳JSON

    • 1μg (R: reducing condition).

  • ELISA

    • Immobilized NCAM-1/CD56 Fc Chimera Protein, Human (Cat. No. UA010813) at 2.0μg/mL (100μL/well) can bind Biotinylated Lorvotuzumab with EC50 of 8.22-12.4 ng/mL.

    • Immobilized NCAM-1/CD56 Fc Chimera Protein, Human (Cat. No. UA010813) at 1.0μg/mL (100μL/well) can bind NCAM-1/CD56 Mouse mAb (S-577-58) (Cat. No. S0B0382) with EC50 of 2.37-3.64 ng/mL.