Lys56-Met219 with His Tag at C-Terminus
22-23kDa (Reducing)
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Fu S, Qian M, Yuan Z, Su S, Ma F, Li F, Xu Z. A new perspective on selenium's impact on renal function: European population-based analysis of plasma proteome-mediated Mendelian randomization study. Front Endocrinol (Lausanne). 2024 Sep 12;15:1410463.
The transmembrane E3 ubiquitin ligase, Zinc and Ring Finger 3 (ZNRF3), serves as a negative feedback regulator of Wnt signaling. ZNRF3 is associated with the Wnt receptor complex and inhibits Wnt signaling by promoting the turnover of Frizzled and LRP6. Additionally, ZNRF3 functions as a tumor suppressor in the intestinal stem cell compartment by inhibiting the Wnt signaling pathway.
CM5 Chip captured RSPO3 Protein, Human (Cat. No. UA040025), can bind ZNRF3 His Tag Protein, Human (Cat. No. UA011107) with an affinity constant of 0.42μM as determined in SPR assay.
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