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Mouse IL-6 Standard for Quantitive Assays

Mouse IL-6 Standard for Quantitive Assays

货号: UA040155-STD
价格: 1000
规格: 1Vial
介绍: -
其他: -
产品规格

  • 物种

    Mouse

  • 分子别名

    Interleukin-6蛋白, IL-6蛋白;Interleukin-6, IL-6, B-Cell Hybridoma Growth Factor, Interleukin HP-1, Il6, Il-6

  • Accession

    P08505

  • 表达序列

    Phe25-Thr211

  • 表达宿主

    E.coli

  • 分子量

    22kDa

  • 纯度

    ＞95% by SDS-PAGE&RP-HPLC

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    1x PBS, pH 7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Cold Spring Harb Perspect Biol. 2014 Sep 4;6(10):a016295.
    2. Cold Spring Harb Perspect Biol. 2018 Aug 1;10(8):a028456.
    3. Biochem J. 2003 Aug 15;374(Pt 1):1-20.

  • 稀释度

背景介绍

  • Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.

  • 生物活性JSON

    • Measured in a cell proliferation assay using Murine B9 cells, the EC50 for this effect is less than 5ng/ml.

  • 电泳JSON

  • 反相高效液相色谱JSON(RP-HPLC)