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BCMA/TNFRSF17 His Tag Protein, Cynomolgus

BCMA/TNFRSF17 His Tag Protein, Cynomolgus

货号: UA011094
价格: 1140
规格: 25μg
介绍: -
其他: -
产品规格

  • 物种

    Cynomolgus

  • 分子别名

    B-Cell Maturation Protein，B-Cell Maturation Factor，B Cell Maturation Antigen，CD269 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 17，TNFRSF13A，CD269，BCM，TNF Receptor Superfamily Member 17，Tumor Necrosis Factor Receptor Superfamily， Member 17，B-Cell Maturation Antigen

  • Accession

    XP_005591343.1

  • 浓度

    ＞95% by SDS-PAGE & SEC-HPLC

  • 表达序列

    Met1-Ala53 with His Tag at the C-Terminus

  • 表达宿主

    HEK293

  • 分子量

    15-18kDa (Reducing)

  • 内毒素含量

    <0.1EU/μg

  • 活性

    Immobilized BCMA/TNFRSF17 His Tag Protein, Cynomolgus (Cat. No. UA011094) at 2.0μg/mL (100μL/well) can bind Biotinylated Human APRIL/TNFSF13 Trimer Protein with EC50 of 0.64-1.04ng/mL.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Gene ID: 608, updated on 18-Aug-2023.

  • 稀释度

背景介绍

  • B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱JSON(SEC-HPLC)

    • The purity of BCMA/TNFRSF17 His Tag Protein, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • ELISA

    • Immobilized BCMA/TNFRSF17 His Tag Protein, Cynomolgus (Cat. No. UA011094) at 2.0μg/mL (100μL/well) can bind Biotinylated Human APRIL/TNFSF13 Trimer Protein with EC50 of 0.64-1.04ng/mL.