Ser19-Lys178
18 kDa (Reducing)
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Gene. 1994 Feb 25;139(2):257-61.
Interleukin-10 (IL-10) is a cytokine with potent anti-inflammatory and immunosuppressive properties that plays a crucial role in regulating immune responses and maintaining immune homeostasis. IL-10 is produced by various immune cells, including macrophages, T cells, and B cells, and functions by inhibiting the production of pro-inflammatory cytokines and suppressing the antigen-presenting and effector functions of immune cells. IL-10 is involved in modulating immune tolerance, preventing excessive inflammation, and promoting tissue repair. In cattle, IL-10 has been studied for its role in regulating immune responses during infections, inflammatory conditions, and autoimmune diseases. Understanding the functions and regulatory mechanisms of bovine IL-10 can provide insights into the immune system of cattle and potential therapeutic strategies for managing immune-related disorders in livestock.
Measured in a cell proliferation assay using murine MC/9 cells. The EC50 this effect is less than 10ng/ml.
2μg (R: reducing condition, N: non-reducing condition).
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