您现在的位置： 首页   -  产品中心   -  免疫学   -   抗体
IL-10 Protein, Canine

IL-10 Protein, Canine

货号: UA040332
价格: 1280
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Canine

  • 分子别名

    Interleukin-10; IL-10; Cytokine synthesis inhibitory factor (CSIF);

  • Accession

    P48411

  • 表达序列

    Ser20-ILe181

  • 表达宿主

    E.coli

  • 分子量

    20 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 < 1.0ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    J Interferon Cytokine Res. 1995 Dec;15(12):1103-9.

  • 稀释度

背景介绍

  • Interleukin-10 (IL-10) is a key immunoregulatory cytokine that plays a crucial role in modulating immune responses and maintaining immune homeostasis. In dogs, IL-10 is produced by various immune cells, including monocytes, macrophages, and T cells, and functions as an anti-inflammatory cytokine by inhibiting the production of pro-inflammatory mediators and suppressing immune cell activation. IL-10 is involved in regulating immune tolerance, controlling excessive inflammation, and promoting tissue repair in dogs. Studies on canine IL-10 have focused on its role in infectious diseases, autoimmune conditions, and cancer, highlighting its importance in canine health and disease.

  • 生物活性JSON

    • Measured in a cell proliferation assay using murine MC/9 cells. The EC50 this effect is less than 1ng/ml.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).