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FGF-5 Protein, Human

FGF-5 Protein, Human

货号: UA040333
价格: 990
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Fibroblast growth factor 5; FGF-5; Heparin-binding growth factor 5 (HBGF-5); Smag-82;

  • 表达序列

    His21-Gly268

  • 表达宿主

    E.coli

  • 分子量

    30 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 < 3.0ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 500mM NaCl, 1mM DTT, pH8.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19679-88.

  • 稀释度

背景介绍

  • Fibroblast Growth Factor 5 (FGF-5) is a member of the fibroblast growth factor (FGF) family, which plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. FGF-5 is primarily known for its involvement in regulating hair growth and cycling. It is expressed in the hair follicles and acts as a negative regulator of hair follicle growth. FGF-5 signaling is essential for the transition between different phases of the hair growth cycle, including the growth phase (anagen), regression phase (catagen), and resting phase (telogen). Dysregulation of FGF-5 expression or activity has been linked to hair loss disorders, such as alopecia, highlighting its importance in hair follicle biology.

  • 生物活性JSON

    • Measured in a cell proliferation assay using Balb/c 3T3 mouse fibroblast cells. The EC50 for this effect is less than 3ng/mL.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).