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IL-28A/IFN-λ2 Protein, Human

货号: UA040337

价格: 820

规格: 10μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

Interferon lambda-2; IFN-lambda-2; Cytokine Zcyto20; Interleukin-28A (IL-28A);
Accession

Q8IZJ0
表达序列

Val26-Val200, with C-terminal 8*His
表达宿主

HEK293
分子量

24 kDa (Reducing)
纯度

>95% by SDS-PAGE and HPLC.
内毒素含量

<0.1EU/μg
活性

Test in progress.
标记

Unconjugated
标签

His Tag
性状

Lyophilized Powder
缓冲体系

PBS, pH 7.4
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

J Virol. 2010 Jun;84(11):5670-7. Epub 2010 Mar 24.

背景介绍

Interleukin-28A (IL-28A), also known as interferon lambda-2 (IFN-λ2), is a member of the type III interferon family. It is produced in response to viral infections and plays a critical role in the innate immune response. IL-28A exhibits antiviral activity by inducing the expression of interferon-stimulated genes (ISGs) and activating immune cells to inhibit viral replication and spread. IL-28A is primarily expressed by immune cells, such as dendritic cells and macrophages, and acts through the IFN-λ receptor complex to exert its antiviral effects. Due to its role in antiviral defense and immune regulation, IL-28A has garnered significant interest as a potential therapeutic target for viral infections, including hepatitis C and respiratory viruses.