您现在的位置： 首页   -  产品中心   -  免疫学   -   抗体
IL-11 Protein, Human

IL-11 Protein, Human

货号: UA040340
价格: 990
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Interleukin-11; IL-11; Adipogenesis inhibitory factor; Oprelvekin;

  • Accession

    P20809

  • 表达序列

    Gly23-Leu199

  • 表达宿主

    E.coli

  • 分子量

    22 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE and HPLC.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 < 1.0ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 200mM NaCl, pH9.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    J Leukoc Biol. 2010 Dec;88(6):1109-17. Epub 2010 Jul 7.

  • 稀释度

背景介绍

  • Interleukin-11 (IL-11) is a cytokine that belongs to the interleukin-6 (IL-6) family of cytokines. IL-11 is produced by various cell types, including stromal cells, fibroblasts, and immune cells, and plays a critical role in regulating hematopoiesis, bone metabolism, and gastrointestinal mucosal integrity. IL-11 exerts its effects through binding to the IL-11 receptor complex, leading to the activation of signaling pathways involved in cell proliferation, differentiation, and survival. IL-11 is known for its anti-inflammatory and tissue-protective properties, making it a potential therapeutic target for various inflammatory and tissue injury-related conditions.

  • 生物活性JSON

    • Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The EC50 for this effect is less than 1ng/ml.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱JSON(RP-HPLC)

    • >95% as determined by RP-HPLC.