Ala21-Lys71
5 kDa (Reducing)
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Science. 2002 Nov 1;298(5595):1025-9.
Beta-defensin 2 is a key component of the innate immune system, known for its antimicrobial properties and immunomodulatory functions. It is produced by various epithelial cells in response to microbial infections and plays a crucial role in host defense against pathogens. Beta-defensin 2 exhibits potent antimicrobial activity against a wide range of microorganisms, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 2 also functions as a chemoattractant for immune cells, such as neutrophils, monocytes, and dendritic cells, promoting their recruitment to sites of infection. Furthermore, beta-defensin 2 can modulate inflammatory responses by regulating cytokine production and promoting wound healing.
2μg (R: reducing condition, N: non-reducing condition).
Measured by its binding ability in a functional ELISA. When Anti-BD-2 Recombinant Antibody is immobilized 0.5µg/mL (100µL/well), Recombinant Mouse BD-2 binds with an EC50 of 0.8-1.0ng/ml.
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