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BD-5 Protein, Human

BD-5 Protein, Human

货号: UA040328
价格: 1080
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Beta-defensin 105; Beta-defensin 5 (BD-5; DEFB-5); Defensin, beta 105;

  • Accession

    Q8NG35

  • 表达序列

    Gly28-Ile78

  • 表达宿主

    E.coli

  • 分子量

    5 kDa (Reducing)

  • 纯度

    >95% by SDS-PAGE.

  • 内毒素含量

    <0.1EU/μg

  • 活性

    EC50 = 0.7-1.2 ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM PB, 250mM NaCl, pH6.5

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Nature. 2003 Apr 3;422(6931):522-6.

  • 稀释度

背景介绍

  • Beta-defensin 5 is a member of the defensin family of antimicrobial peptides that play a crucial role in the innate immune system's defense against pathogens. It is primarily expressed in the gastrointestinal tract, where it contributes to maintaining the mucosal barrier integrity and protecting against microbial invasion. Beta-defensin 5 exhibits potent antimicrobial activity against a wide range of pathogens, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 5 also plays a role in modulating immune responses, promoting wound healing, and maintaining the balance of the gut microbiota.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).

  • ELISA

    • Measured by its binding ability in a functional ELISA. When Anti-BD-5 antibody is immobilized 0.5µg/mL (100µL/well), Recombinant Human BD-5 binds with an EC50 of 0.7-1.2ng/ml.