Arg31-Gln163
17 kDa (Reducing)
PBS, pH7.4
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Cytokine. 2009 Apr;46(1):7-11. Epub 2009 Feb 23.
Interleukin-17F (IL-17F) is a member of the interleukin-17 cytokine family that plays a key role in regulating inflammatory responses and immune reactions. IL-17F is primarily produced by activated T cells, particularly Th17 cells, and acts on various cell types, including epithelial cells, fibroblasts, and immune cells. IL-17F is involved in the pathogenesis of inflammatory and autoimmune diseases, such as asthma, rheumatoid arthritis, and inflammatory bowel disease. It promotes the production of pro-inflammatory cytokines and chemokines, leading to recruitment of immune cells to sites of inflammation and tissue damage.
Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is less than 30ng/ml.
2μg (R: reducing condition, N: non-reducing condition).
>95% as determined by RP-HPLC.
Immobilized IL-17F Protein, Human (Cat. No. UA040308) at 5μg/mL (100μL/well) can bind IL-17 RA Protein, Human (Cat. No. UA040024) with EC50 of 0.73-0.88 μg/mL.
您现在的位置：
