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SDF-1β/CXCL12 Protein, Human

货号: UA040317

价格: 1180

规格: 10μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

Stromal cell-derived factor 1; SDF-1; hSDF-1; C-X-C motif chemokine 12; Intercrine reduced in hepatomas (IRH hIRH); Pre-B cell growth-stimulating factor (PBSF);
Accession

P48061
表达序列

Lys22-Met93
表达宿主

E.coli
分子量

10 kDa (Reducing)
纯度

>95% by SDS-PAGE.
内毒素含量

<0.1EU/μg
活性

Test in progress.
标记

Unconjugated
标签

No Tag
性状

Lyophilized Powder
缓冲体系

PBS, pH7.0
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

Nature. 2001 Mar 1;410(6824):50-6.

背景介绍

Stromal Cell-Derived Factor 1 beta (SDF-1β), also known as CXCL12, is a chemokine protein that plays a crucial role in immune cell trafficking, hematopoiesis, and tissue repair. SDF-1β is produced by stromal cells, endothelial cells, and fibroblasts, and acts as a chemoattractant for a variety of immune cells, including lymphocytes, monocytes, and hematopoietic stem cells. SDF-1β binds to its receptor, CXCR4, and regulates cell migration, adhesion, and survival. This chemokine is involved in various physiological and pathological processes, such as inflammation, angiogenesis, and cancer metastasis.