Asp20-Val193, with C-terminal 8*His
25-30 kDa (Reducing)
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Nat Immunol. 2003 Jan;4(1):63-8. Epub 2002 Dec 2.
Interferon lambda 2 (IFN-λ2), also known as interleukin-28A (IL-28A), is a type III interferon that belongs to the interferon lambda family. IFN-λ2 is produced in response to viral infections and plays a crucial role in the innate immune response against viruses. It exerts antiviral effects by inducing the expression of interferon-stimulated genes (ISGs) that inhibit viral replication and spread. IFN-λ2 signals through the IFN-λ receptor complex, which consists of IL-10R2 and IL-28Rα subunits, leading to the activation of downstream signaling pathways involved in antiviral defense. IFN-λ2 is considered a promising therapeutic agent for the treatment of viral infections due to its potent antiviral properties and reduced potential for side effects compared to type I interferons.
2μg (R: reducing condition, N: non-reducing condition).
>95% as determined by SEC-HPLC.
您现在的位置：
