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CCL14a/HCC-1(66aa) Protein, Human

货号: UA040307

价格: 820

规格: 10μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

C-C motif chemokine 14; Chemokine CC-1/CC-3 (HCC-1/HCC-3); HCC-1(1-74); NCC-2; Small-inducible cytokine A14;
Accession

Q16627
表达序列

Gly28-Asn93
表达宿主

E.coli
分子量

7.8 kDa (Reducing)
纯度

>95% by SDS-PAGE and HPLC.
内毒素含量

<0.1EU/μg
活性

Test in progress.
标记

Unconjugated
标签

No Tag
性状

Lyophilized Powder
缓冲体系

20mM PB, 500mM NaCl, pH7.0
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

BMC Genomics. 2008 May 15:9:222.

背景介绍

CCL14a, also known as HCC-1 (Hematopoietic Cell-Derived CC Chemokine 1), is a chemokine belonging to the CC chemokine family. It is involved in immune regulation and inflammation. CCL14a/HCC-1 is produced by various cell types, including monocytes, macrophages, and dendritic cells, in response to inflammatory stimuli.
CCL14a/HCC-1 functions by binding to specific chemokine receptors on target cells, such as CCR1 and CCR5, to induce chemotaxis and activation of immune cells. It plays a role in recruiting leukocytes to sites of inflammation and modulating immune responses.
Research has shown that CCL14a/HCC-1 is implicated in various physiological and pathological processes, including immune cell trafficking, inflammatory diseases, and cancer. Understanding the role of CCL14a/HCC-1 in these processes may provide insights into potential therapeutic strategies for targeting this chemokine in the treatment of related conditions.