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PSCA His Tag Protein, Mouse

PSCA His Tag Protein, Mouse

货号: UA011068
价格: 1800
规格: 25μg
介绍: -
其他: -
产品规格

  • 物种

    Mouse

  • 分子别名

    Prostate stem cell antigen，UNQ206/PRO232，PRO232

  • Accession

    P57096

  • 表达序列

    Leu21-Asn95, with C-terminal His

  • 表达宿主

    HEK293

  • 分子量

    20-30kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE &＞90% by SEC-HPLC

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, 5% trehalose, PH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Reiter RE, Gu Z, Watabe T, Thomas G, Szigeti K, Davis E, Wahl M, Nisitani S, Yamashiro J, Le Beau MM, Loda M, Witte ON. Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1735-40.
    2.Yang D, Holt GE, Velders MP, Kwon ED, Kast WM. Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice. Cancer Res. 2001 Aug 1;61(15):5857-60.

  • 稀释度

背景介绍

  • Prostate stem cell antigen (PSCA), a cell-membrane glycoprotein composed of 123 amino acids, is frequently expressed in prostate cancer. Mouse PSCA (mPSCA) exhibits 65% homology with human PSCA at both the nucleotide and amino acid levels. The knockdown of PSCA has been shown to induce epithelial-mesenchymal transition (EMT) and to reduce the metastatic potential of DU145 cells, indicating a significant role for PSCA in the carcinogenesis and progression of prostate cancer.

  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱JSON(SEC-HPLC)

    • The purity of PSCA His Tag Protein, Mouse is more than 90% determined by SEC-HPLC.