Predicted MW of 49.80 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
＞95% by SDS-PAGE
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Death Receptor 3 (DR3), also known as TNFRSF25, TRAMP, LARD, or WSL-1, is a death-domain-containing TNF-family receptor that, like its closest paralog TNFR1, binds the adaptor molecule TRADD through its cytoplasmic death domain. TRADD recruitment endows DR3 with dual-signaling capability to activate NF−κB and MAP-kinase signaling or alternatively trigger caspase activation and programmed cell death.
Human DR3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Immobilized Human TNFSF15 Trimer, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human DR3, hFc Tag with the EC50 of 0.67μg/ml determined by ELISA.
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