25 kDa (Reducing)
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
1. Alina G Sofronescu. Cardiovasc Res. 2010 Jul 1;87(1).
Fibroblast growth factors (Fgfs), proteins of 150~300 amino acids, play diverse roles in development, repair and metabolism. The human/mouse Fgf family comprises twenty-two members. Most Fgfs mediate biological responses by binding to and activating Fgf receptors (Fgfrs) in a paracrine manner. Among paracrine Fgfs, Fgf16 is predominantly expressed in the heart. Fgf16 expression is weakly detected in the embryonic heart and much more abundant at adult stages than embryonic stages. These findings indicate potential roles in the heart.
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The EC50 for this effect is less than 5ng/ml.
>95% as determined by RP-HPLC.