Ala20-Glu764, with C-terminal His
100-130kDa (Reducing)
PBS, PH7.4, 5% trehalose
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1.Lian, L. et al. (2019) BMC Cancer. 19:183.
2.Hu, C. et al. (2019) Onco. Targets Ther. 12:933.
3.Gao, F. et al. (2020) Curr. Cancer Drug Targets. 20:3.
Vascular endothelial Growth Factor Receptor 2 (VEGFR2), also known as FLK-1, KDR, and CD309, is a type I single-pass membrane receptor，and is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). Mature VEGFR2 contains a 745 amino acid extracelluar domain with seven immunoglobulin-like repeats, 21 transmembrane domain and 571 cytoplasmic domain. Within the extracellular domain, human VEGFR2 shares 80% homology with that of mouse and rat. VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF. In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions.
1μg (R: reducing condition, N: non-reducing condition).
The purity of VEGF R2/Flk-1/KDR His Tag Protein, Rhesus macaque is greater than 95% as determined by SEC-HPLC.
Immobilized VEGF R2/Flk-1/KDR His Tag Protein, Rhesus macaque (Cat. No. UA010877) at 2μg/mL (100μL/well) can bind Olinvacimab (Cat. No. UA011020) with EC50 of 3.11-3.93 ng/ml.
Immobilized VEGF R2/Flk-1/KDR His Tag Protein, Rhesus macaque (Cat. No. UA010877) at 2.0μg/mL (100μL/well) can bind Olinvacimab (Cat. No. UA011020) with EC50 of 3.11-3.93ng/mL.
您现在的位置：