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Ephrin-A1 Fc Chimera Protein, Human

Ephrin-A1 Fc Chimera Protein, Human

货号: UA011030
价格: 1000
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    EFNA1, LERK-1, TNFAIP4, EPLG1, B61, ECKLG, EFL1
  • Accession

    P20827-1
  • 表达序列

    Asp19-Ser182, with hIgG Fc

  • 表达宿主

    HEK293
  • 分子量

    51-55 kDa (R)

  • 纯度

    >95% by SDS-PAGE & RP-HPLC
  • 活性

    Immobilized Biotinylated EphA2 His&Avi Tag Protein, Human (Cat. No. UA010833) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Ephrin-A1 Fc Chimera Protein, Human (Cat. No. UA011030) with EC50 of 1.20-1.74 ng/ml.
  • 标记

    Unconjugated
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Singh PK, Rybak JA, Schuck RJ, Barrera FN, Smith AW. Phosphatidylinositol (4,5)-bisphosphate drives the formation of EGFR and EphA2 complexes. bioRxiv [Preprint]. 2024 May 4:2024.05.03.592400. PMID: 38746348; 

  • 稀释度

背景介绍
  • Ephrin-A1 (EFNA1) is also known as EPLG1, LERK1, TNFAIP4, Immediate early response protein B61, which belongs to the ephrin family. EFNA1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA1 is cell surface GPI-bound ligand for Eph receptors, and is a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱JSON(RP-HPLC)

    • The purity of Ephrin-A1 Fc Chimera Protein, Human is greater than 95% as determined by RP-HPLC.

  • ELISA

    • Immobilized Biotinylated EphA2 His&Avi Tag Protein, Human (Cat. No. UA010833) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Ephrin-A1 Fc Chimera Protein, Human (Cat. No. UA011030) with EC50 of 1.20-1.74 ng/ml.

    • Immobilized EphA2 His Tag, Human  (Cat. No. UA010580) at 2μg/mL (100μL/well) can bind Ephrin-A1 Fc Chimera Protein, Human (Cat. No. UA011030) with EC50 of 0.70-1.00 ng/ml.