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CD117/c-Kit His Tag Protein, Cynomolgus

CD117/c-Kit His Tag Protein, Cynomolgus

货号: UA010933
价格: 1480
规格: 25μg
介绍: -
其他: -
产品规格

  • 物种

    Cynomolgus

  • 分子别名

    CD117, SCFR, c-Kit, KIT

  • Accession

    XP_005555332.1

  • 表达序列

    Gln26-Pro520, with C-terminal His

  • 表达宿主

    HEK293

  • 分子量

    75-95kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE &＞SEC-HPLC

  • 内毒素含量

    <0.1EU/μg

  • 活性

    Immobilized SCF Protein, Human (Cat. No. UA040138) at 2.0μg/mL (100μL/well) can bind CD117/c-Kit His Tag Protein, Cynomolgus (Cat. No. UA010933) with EC50 of 2.93-3.95 μg/mL.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, 5% trehalose, PH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Wang H, Ni R, Wang A, Liu B. CD117 expression predicted FLT3 mutation in T-cell acute lymphoblastic leukemia. EJHaem. 2024 Feb 18;5(1):294-295.
    2. Jiang YJ, Zhang CF, Wang HX, Zhao L, Zhang FF, Han XH. [Clinical Significance of Genetic and Molecular Changes in Primary Myeloid Sarcoma]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2024 Feb;32(1):27-32. Chinese.

  • 稀释度

背景介绍

  • Mast/stem cell growth factor receptor Kit (c-Kit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.

  • 电泳JSON

  • 体积排阻色谱JSON(SEC-HPLC)

  • ELISA

    • Immobilized SCF Protein, Human (Cat. No. UA040138) at 2.0μg/mL (100μL/well) can bind CD117/c-Kit His Tag Protein, Cynomolgus (Cat. No. UA010933) with EC50 of 2.93-3.95 μg/mL.