Cys24-Glu540, with C-hIgG Fc
95-110kDa (Reducing)
PBS, 5% trehalose, PH7.4
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1. Pérez-Martínez L, Romero L, Verdugo-Sivianes EM, Muñoz-Galván S, Rubio-Mediavilla S, Amiama-Roig A, Carnero A, Blanco JR. Role of maraviroc and/or rapamycin in the liver of IL10 KO mice with frailty syndrome. PLoS One. 2024 Jan 10;19(1): e0286201. l. (2008) Nat.
2. Chan BC, Li P, Tsang MS, Sung JC, Kwong KW, Zheng T, Hon SS, Lau CP, Ho RC, Chen F, Lau CB, Leung PC, Wong CK. Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge. and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection. J Leukoc Biol. 2024 Jan 5;115(1):177-189.
IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Immobilized IL-12, Human(Cat. No. UA040200) at 2.0μg/mL (100μL/well) can bind IL-12 R beta 1 Fc Chimera, Human(Cat. No. UA010956) with EC50 of 0.18-0.23 μg/ mL.
Immobilized IL-12/IL-23 p40 Monomer Protein, Mouse (Cat. No. UA040455) at 2.0μg/mL (100μL/well) can bind IL-12 R beta 1 Fc Chimera Protein, Human (Cat. No. UA010956) with EC50 of 0.06-0.17μg/mL.
Immobilized IL-12/IL-23 p40 Homodimer Protein, Mouse (Cat. No. UA040458) at 2.0μg/mL (100μL/well) can bind IL-12 R beta 1 Fc Chimera Protein, Human (Cat. No. UA010956) with EC50 of 28.03-43.41ng/mL.
Immobilized IL-12/IL-23 p40 Monomer Protein, Rat (Cat. No. UA040456) at 2.0μg/mL (100μL/well) can bind IL-12 R beta 1 Fc Chimera Protein, Human (Cat. No. UA010956) with EC50 of 9.08-37.10ng/mL.
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